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PIMSO 2025 - Science - Secondary 4 - National Round Question 4

PIMSO Science · PIMSO 2025 - Science - Secondary 4 - National Round

Question 4

The following sequences show a partial segment of a DNA, wherein the first sequence encodes for the wild-type hypothetical protein, while the second sequence contains a mutation. What could be inferred with the protein encoded by the mutated DNA? #1 5’- GTGATAGCTTTGATAAGCGAAAGTTTGGAGAAGCTG-3’ #2 5’- GTGATAGCTTTGATAAGCTAAAGTTTGGAGAAGCTG-3’ Source: https://www.khanacademy.org/

Question illustration

Editorial convention: treat the displayed 5′→3′ sequences as coding strands, with codons starting at the first shown base.
  1. Protein from mutated DNA has one different amino acid.
  2. Protein from mutated DNA has a shorter amino acid sequence.
  3. Protein from mutated DNA has a longer amino acid sequence.
  4. Protein from mutated DNA has a completely different amino acid sequence.